Fare Guide

Estimated lowest fares found within 7 days

Cheapest Airline Frontier Airlines

The cheapest airline(s) flying from Buffalo to San Francisco is Frontier Airlines.

  • Frontier Airlines Frontier Airlines
  • American Airlines American Airlines
  • Delta Air Lines Delta Air Lines
  • JetBlue Airways JetBlue Airways
  • United Airlines United Airlines
  • Alaska Airlines Alaska Airlines
  • Southwest Airlines Southwest Airlines
Cheapest Month December

Travel Period: October 2024 - September 2025

The cheapest month(s) to fly from Buffalo to San Francisco is December.

  • Oct 2024
  • Nov 2024
  • Dec 2024
  • Jan 2025
  • Feb 2025
  • Mar 2025
  • Apr 2025
  • May 2025
  • Jun 2025
  • Jul 2025
  • Aug 2025
  • Sep 2025
Cheapest Day of the Week Wednesday

The cheapest day(s) of the week to fly from Buffalo to San Francisco is Wednesday.

  • Sun Sunday
  • Mon Monday
  • Tue Tuesday
  • Wed Wednesday
  • Thu Thursday
  • Fri Friday
  • Sat Saturday

Flight Schedules

Last Updated: Mon, 2 Sep, 2024

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      • Availability
        • M
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      • 06:00 BUF
        14:15 SFO
        11Hrs, 15m 1 Stop (JFK)
      • BUFBuffalo Airport 06:00 - SFO 14:15 11h 15m 1 Stop (JFK) New York City
      • BUFBuffalo Airport 06:00
        JFKNew York John F. Kennedy International Airport 11:00
      • JFKNew York John F. Kennedy International Airport 07:28
        SFOSan Francisco International Airport 14:15
      • 11h 15m (3h 32m)
      • 1 Stop JFK · New York City 3h 32m
      • JetBlue Airways (B6 201)Airbus A220 300
        JetBlue Airways (B6 1515)Airbus Industrie A321
      • JetBlue Airways (B6 201)
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        • T
        • F
        • -
        • S
      • 06:00 BUF
        14:16 SFO
        11Hrs, 16m 1 Stop (JFK)
      • BUFBuffalo Airport 06:00 - SFO 14:16 11h 16m 1 Stop (JFK) New York City
      • BUFBuffalo Airport 06:00
        JFKNew York John F. Kennedy International Airport 11:00
      • JFKNew York John F. Kennedy International Airport 07:28
        SFOSan Francisco International Airport 14:16
      • 11h 16m (3h 32m)
      • 1 Stop JFK · New York City 3h 32m
      • JetBlue Airways (B6 201)Airbus A220 300
        JetBlue Airways (B6 1515)Airbus Industrie A321
      • JetBlue Airways (B6 201)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 06:00 BUF
        11:39 SFO
        8Hrs, 39m 1 Stop (EWR)
      • BUFBuffalo Airport 06:00 - SFO 11:39 8h 39m 1 Stop (EWR) New York City
      • BUFBuffalo Airport 06:00
        EWRNewark Liberty International Airport 08:35
      • EWRNewark Liberty International Airport 07:24
        SFOSan Francisco International Airport 11:39
      • 8h 39m (1h 11m)
      • 1 Stop EWR · New York City 1h 11m
      • United Airlines (UA 1598)Airbus
        United Airlines (UA 1582)Boeing 777
      • United Airlines (UA 1598)
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        • F
        • -
        • -
      • 06:00 BUF
        11:55 SFO
        8Hrs, 55m 1 Stop (EWR)
      • BUFBuffalo Airport 06:00 - SFO 11:55 8h 55m 1 Stop (EWR) New York City
      • BUFBuffalo Airport 06:00
        EWRNewark Liberty International Airport 08:35
      • EWRNewark Liberty International Airport 07:24
        SFOSan Francisco International Airport 11:55
      • 8h 55m (1h 11m)
      • 1 Stop EWR · New York City 1h 11m
      • United Airlines (UA 1598)Airbus
        United Airlines (UA 1582)Boeing 757 200 Series
      • United Airlines (UA 1598)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 06:00 BUF
        11:55 SFO
        8Hrs, 55m 1 Stop (EWR)
      • BUFBuffalo Airport 06:00 - SFO 11:55 8h 55m 1 Stop (EWR) New York City
      • BUFBuffalo Airport 06:00
        EWRNewark Liberty International Airport 08:35
      • EWRNewark Liberty International Airport 07:24
        SFOSan Francisco International Airport 11:55
      • 8h 55m (1h 11m)
      • 1 Stop EWR · New York City 1h 11m
      • United Airlines (UA 1598)Boeing 737 700
        United Airlines (UA 1582)Boeing 757 200 Series
      • United Airlines (UA 1598)
        • -
        • -
        • -
        • -
        • -
        • -
        • S
      • 06:00 BUF
        12:04 SFO
        9Hrs, 04m 1 Stop (ATL)
      • BUFBuffalo Airport 06:00 - SFO 12:04 9h 04m 1 Stop (ATL) Atlanta
      • BUFBuffalo Airport 06:00
        ATLAtlanta Hartsfield-Jackson Intl Airport 10:05
      • ATLAtlanta Hartsfield-Jackson Intl Airport 08:08
        SFOSan Francisco International Airport 12:04
      • 9h 04m (1h 57m)
      • 1 Stop ATL · Atlanta 1h 57m
      • Delta Air Lines (DL 2664)Airbus
        Delta Air Lines (DL 531)Boeing 757 300 Series
      • Delta Air Lines (DL 2664)
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        • S
      • 11:00 STL
        07:15 BWI
        10Hrs, 05m 1 Stop (SFO)
      • STLSt Louis Lambert Intl Airport 11:00 - BWI 07:15 10h 05m 1 Stop (SFO) San Francisco
      • STLSt Louis Lambert Intl Airport 11:00
        BUFBuffalo Airport 06:00
      • SFOSan Francisco International Airport 13:05
        BWIBaltimore Washington International Airport 07:15
      • 10h 05m (2h 25m)
      • 1 Stop SFO · San Francisco 2h 25m
      • Southwest Airlines (WN 1257)Boeing 737 Max 8 Passenger
        Southwest Airlines (WN 4468)Boeing 737 800
      • Southwest Airlines (WN 1257)
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        • -
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        • -
        • -
      • 06:00 BUF
        13:20 SFO
        10Hrs, 20m 1 Stop (EWR)
      • BUFBuffalo Airport 06:00 - SFO 13:20 10h 20m 1 Stop (EWR) New York City
      • BUFBuffalo Airport 06:00
        EWRNewark Liberty International Airport 10:00
      • EWRNewark Liberty International Airport 07:24
        SFOSan Francisco International Airport 13:20
      • 10h 20m (2h 36m)
      • 1 Stop EWR · New York City 2h 36m
      • United Airlines (UA 1598)Airbus
        United Airlines (UA 2428)Boeing 757 200 Series
      • United Airlines (UA 1598)
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        • F
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        • -
      • 06:00 BUF
        13:20 SFO
        10Hrs, 20m 1 Stop (EWR)
      • BUFBuffalo Airport 06:00 - SFO 13:20 10h 20m 1 Stop (EWR) New York City
      • BUFBuffalo Airport 06:00
        EWRNewark Liberty International Airport 10:00
      • EWRNewark Liberty International Airport 07:24
        SFOSan Francisco International Airport 13:20
      • 10h 20m (2h 36m)
      • 1 Stop EWR · New York City 2h 36m
      • United Airlines (UA 1598)Boeing 737 700
        United Airlines (UA 2428)Boeing 757 200 Series
      • United Airlines (UA 1598)
        • -
        • -
        • -
        • -
        • -
        • -
        • S
      • 06:00 BUF
        13:21 SFO
        10Hrs, 21m 1 Stop (JFK)
      • BUFBuffalo Airport 06:00 - SFO 13:21 10h 21m 1 Stop (JFK) New York City
      • BUFBuffalo Airport 06:00
        JFKNew York John F. Kennedy International Airport 09:55
      • JFKNew York John F. Kennedy International Airport 07:28
        SFOSan Francisco International Airport 13:21
      • 10h 21m (2h 27m)
      • 1 Stop JFK · New York City 2h 27m
      • JetBlue Airways (B6 201)Airbus A220 300
        JetBlue Airways (B6 115)Airbus Industrie A321
      • JetBlue Airways (B6 201)
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        • S
      • 06:00 BUF
        13:57 SFO
        10Hrs, 57m 1 Stop (ATL)
      • BUFBuffalo Airport 06:00 - SFO 13:57 10h 57m 1 Stop (ATL) Atlanta
      • BUFBuffalo Airport 06:00
        ATLAtlanta Hartsfield-Jackson Intl Airport 12:04
      • ATLAtlanta Hartsfield-Jackson Intl Airport 08:08
        SFOSan Francisco International Airport 13:57
      • 10h 57m (3h 56m)
      • 1 Stop ATL · Atlanta 3h 56m
      • Delta Air Lines (DL 2664)Airbus
        Delta Air Lines (DL 533)Boeing 757 300 Series
      • Delta Air Lines (DL 2664)
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        • S
      • 11:00 LAX
        06:40 MDW
        9Hrs, 15m 1 Stop (SFO)
      • LAXLos Angeles International Airport 11:00 - MDW 06:40 9h 15m 1 Stop (SFO) San Francisco
      • LAXLos Angeles International Airport 11:00
        BUFBuffalo Airport 06:05
      • SFOSan Francisco International Airport 12:20
        MDWChicago Midway Airport 06:40
      • 9h 15m (2h 05m)
      • 1 Stop SFO · San Francisco 2h 05m
      • Southwest Airlines (WN 4960)Boeing 737 700
        Southwest Airlines (WN 2087)Boeing 737 800
      • Southwest Airlines (WN 4960)
        • -
        • -
        • -
        • -
        • -
        • -
        • S
      • 11:15 LAS
        06:40 MDW
        9Hrs, 45m 1 Stop (SFO)
      • LASLas Vegas McCarran International Airport 11:15 - MDW 06:40 9h 45m 1 Stop (SFO) San Francisco
      • LASLas Vegas McCarran International Airport 11:15
        BUFBuffalo Airport 06:05
      • SFOSan Francisco International Airport 12:50
        MDWChicago Midway Airport 06:40
      • 9h 45m (2h 45m)
      • 1 Stop SFO · San Francisco 2h 45m
      • Southwest Airlines (WN 3115)Boeing 737 800
        Southwest Airlines (WN 2087)Boeing 737 800
      • Southwest Airlines (WN 3115)
        • -
        • -
        • -
        • -
        • -
        • -
        • S
      • 06:09 BUF
        11:17 SFO
        8Hrs, 08m 1 Stop (PHL)
      • BUFBuffalo Airport 06:09 - SFO 11:17 8h 08m 1 Stop (PHL) Philadelphia
      • BUFBuffalo Airport 06:09
        PHLPhiladelphia International Airport 08:19
      • PHLPhiladelphia International Airport 07:29
        SFOSan Francisco International Airport 11:17
      • 8h 08m (50m)
      • 1 Stop PHL · Philadelphia 50m
      • American Airlines (AA 5165)Canadair Regional
        American Airlines (AA 2407)Airbus A321 Neo
      • American Airlines (AA 5165)
        • M
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        • F
        • -
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      • 06:15 BUF
        10:22 SFO
        7Hrs, 07m 1 Stop (DTW)
      • BUFBuffalo Airport 06:15 - SFO 10:22 7h 07m 1 Stop (DTW) Detroit
      • BUFBuffalo Airport 06:15
        DTWDetroit Wayne County 08:25
      • DTWDetroit Wayne County 07:25
        SFOSan Francisco International Airport 10:22
      • 7h 07m (1h)
      • 1 Stop DTW · Detroit 1h
      • Delta Air Lines (DL 2285)Airbus
        Delta Air Lines (DL 361)Boeing 757 300 Series
      • Delta Air Lines (DL 2285)
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        • F
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        • S
      • 06:15 BUF
        11:01 SFO
        7Hrs, 46m 1 Stop (IAD)
      • BUFBuffalo Airport 06:15 - SFO 11:01 7h 46m 1 Stop (IAD) Washington
      • BUFBuffalo Airport 06:15
        IADWashington Dulles International Airport 08:21
      • IADWashington Dulles International Airport 07:32
        SFOSan Francisco International Airport 11:01
      • 7h 46m (49m)
      • 1 Stop IAD · Washington 49m
      • United Airlines (UA 6238)Embraer 175
        United Airlines (UA 1116)Boeing 777
      • United Airlines (UA 6238)
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        • S
      • 11:35 SLC
        07:25 DTW
        9Hrs, 22m 1 Stop (SFO)
      • SLCSalt Lake City Airport 11:35 - DTW 07:25 9h 22m 1 Stop (SFO) San Francisco
      • SLCSalt Lake City Airport 11:35
        BUFBuffalo Airport 06:15
      • SFOSan Francisco International Airport 12:37
        DTWDetroit Wayne County 07:25
      • 9h 22m (2h 10m)
      • 1 Stop SFO · San Francisco 2h 10m
      • Delta Air Lines (DL 902)Airbus
        Delta Air Lines (DL 2285)Airbus
      • Delta Air Lines (DL 902)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 11:35 SLC
        07:25 DTW
        9Hrs, 23m 1 Stop (SFO)
      • SLCSalt Lake City Airport 11:35 - DTW 07:25 9h 23m 1 Stop (SFO) San Francisco
      • SLCSalt Lake City Airport 11:35
        BUFBuffalo Airport 06:15
      • SFOSan Francisco International Airport 12:38
        DTWDetroit Wayne County 07:25
      • 9h 23m (2h 10m)
      • 1 Stop SFO · San Francisco 2h 10m
      • Delta Air Lines (DL 902)Boeing 737 900
        Delta Air Lines (DL 2285)Airbus
      • Delta Air Lines (DL 902)
        • M
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        • T
        • F
        • -
        • S
      • 10:40 ORD
        07:32 IAD
        9Hrs, 53m 1 Stop (SFO)
      • ORDChicago O'Hare International Airport 10:40 - IAD 07:32 9h 53m 1 Stop (SFO) San Francisco
      • ORDChicago O'Hare International Airport 10:40
        BUFBuffalo Airport 06:15
      • SFOSan Francisco International Airport 13:08
        IADWashington Dulles International Airport 07:32
      • 9h 53m (1h 57m)
      • 1 Stop SFO · San Francisco 1h 57m
      • United Airlines (UA 343)Boeing 777
        United Airlines (UA 6238)Embraer 175
      • United Airlines (UA 343)
        • -
        • -
        • -
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        • F
        • -
        • -
      • 11:00 MSP
        07:25 DTW
        9Hrs, 57m 1 Stop (SFO)
      • MSPMinneapolis International Airport 11:00 - DTW 07:25 9h 57m 1 Stop (SFO) San Francisco
      • MSPMinneapolis International Airport 11:00
        BUFBuffalo Airport 06:15
      • SFOSan Francisco International Airport 13:12
        DTWDetroit Wayne County 07:25
      • 9h 57m (2h 39m)
      • 1 Stop SFO · San Francisco 2h 39m
      • Delta Air Lines (DL 2074)Boeing 737 900
        Delta Air Lines (DL 2285)Airbus
      • Delta Air Lines (DL 2074)
        • M
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        • F
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        • S
      • 11:36 DEN
        07:32 IAD
        10Hrs, 03m 1 Stop (SFO)
      • DENDenver Intl Airport 11:36 - IAD 07:32 10h 03m 1 Stop (SFO) San Francisco
      • DENDenver Intl Airport 11:36
        BUFBuffalo Airport 06:15
      • SFOSan Francisco International Airport 13:18
        IADWashington Dulles International Airport 07:32
      • 10h 03m (2h 08m)
      • 1 Stop SFO · San Francisco 2h 08m
      • United Airlines (UA 1561)Boeing 737 900
        United Airlines (UA 6238)Embraer 175
      • United Airlines (UA 1561)
        • -
        • -
        • -
        • -
        • -
        • -
        • S
      • 11:36 DEN
        07:32 IAD
        10Hrs, 03m 1 Stop (SFO)
      • DENDenver Intl Airport 11:36 - IAD 07:32 10h 03m 1 Stop (SFO) San Francisco
      • DENDenver Intl Airport 11:36
        BUFBuffalo Airport 06:15
      • SFOSan Francisco International Airport 13:18
        IADWashington Dulles International Airport 07:32
      • 10h 03m (2h 19m)
      • 1 Stop SFO · San Francisco 2h 19m
      • United Airlines (UA 1561)Boeing 737 900
        United Airlines (UA 6238)Embraer 175
      • United Airlines (UA 1561)
        • M
        • T
        • W
        • T
        • F
        • S
        • -
      • 10:40 ORD
        07:32 IAD
        10Hrs, 05m 1 Stop (SFO)
      • ORDChicago O'Hare International Airport 10:40 - IAD 07:32 10h 05m 1 Stop (SFO) San Francisco
      • ORDChicago O'Hare International Airport 10:40
        BUFBuffalo Airport 06:15
      • SFOSan Francisco International Airport 13:20
        IADWashington Dulles International Airport 07:32
      • 10h 05m (1h 57m)
      • 1 Stop SFO · San Francisco 1h 57m
      • United Airlines (UA 343)Airbus A321 Neo
        United Airlines (UA 6238)Embraer 175
      • United Airlines (UA 343)
        • M
        • T
        • W
        • -
        • -
        • S
        • S
      • 11:46 LAS
        07:41 DCA
        10Hrs, 05m 1 Stop (SFO)
      • LASLas Vegas McCarran International Airport 11:46 - DCA 07:41 10h 05m 1 Stop (SFO) San Francisco
      • LASLas Vegas McCarran International Airport 11:46
        BUFBuffalo Airport 06:22
      • SFOSan Francisco International Airport 13:27
        DCAWashington Ronald Reagan National Airport 07:41
      • 10h 05m (1h 41m)
      • 1 Stop SFO · San Francisco 1h 41m
      • Alaska Airlines (AS 3391)Embraer Emb 175
        American Airlines (AA 5243)Crj 700 Canadair Regional
      • Alaska Airlines (AS 3391)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 06:35 BUF
        11:55 SFO
        8Hrs, 20m 1 Stop (DEN)
      • BUFBuffalo Airport 06:35 - SFO 11:55 8h 20m 1 Stop (DEN) Denver
      • BUFBuffalo Airport 06:35
        DENDenver Intl Airport 10:15
      • DENDenver Intl Airport 08:00
        SFOSan Francisco International Airport 11:55
      • 8h 20m (2h 15m)
      • 1 Stop DEN · Denver 2h 15m
      • Southwest Airlines (WN 621)Boeing 737 800
        Southwest Airlines (WN 549)Boeing 737 800
      • Southwest Airlines (WN 621)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 06:45 BUF
        12:45 SFO
        9Hrs, 00m 1 Stop (DFW)
      • BUFBuffalo Airport 06:45 - SFO 12:45 9h 1 Stop (DFW) Dallas
      • BUFBuffalo Airport 06:45
        DFWDallas/Fort Worth Intl Airport 11:00
      • DFWDallas/Fort Worth Intl Airport 09:04
        SFOSan Francisco International Airport 12:45
      • 9h (1h 56m)
      • 1 Stop DFW · Dallas 1h 56m
      • American Airlines (AA 576)Airbus
        American Airlines (AA 2387)Airbus
      • American Airlines (AA 576)
        • -
        • -
        • -
        • -
        • F
        • -
        • -
      • 06:45 BUF
        12:45 SFO
        9Hrs, 00m 1 Stop (DFW)
      • BUFBuffalo Airport 06:45 - SFO 12:45 9h 1 Stop (DFW) Dallas
      • BUFBuffalo Airport 06:45
        DFWDallas/Fort Worth Intl Airport 11:00
      • DFWDallas/Fort Worth Intl Airport 09:04
        SFOSan Francisco International Airport 12:45
      • 9h (1h 56m)
      • 1 Stop DFW · Dallas 1h 56m
      • American Airlines (AA 576)Airbus
        American Airlines (AA 2387)Airbus
      • American Airlines (AA 576)
        • M
        • T
        • W
        • -
        • -
        • S
        • -
      • 06:45 BUF
        13:00 SFO
        9Hrs, 15m 1 Stop (DFW)
      • BUFBuffalo Airport 06:45 - SFO 13:00 9h 15m 1 Stop (DFW) Dallas
      • BUFBuffalo Airport 06:45
        DFWDallas/Fort Worth Intl Airport 11:15
      • DFWDallas/Fort Worth Intl Airport 09:04
        SFOSan Francisco International Airport 13:00
      • 9h 15m (2h 11m)
      • 1 Stop DFW · Dallas 2h 11m
      • American Airlines (AA 576)Airbus
        American Airlines (AA 2387)Airbus
      • American Airlines (AA 576)
        • -
        • -
        • -
        • T
        • -
        • -
        • S
      • 12:15 LAX
        09:04 DFW
        9Hrs, 58m 1 Stop (SFO)
      • LAXLos Angeles International Airport 12:15 - DFW 09:04 9h 58m 1 Stop (SFO) San Francisco
      • LAXLos Angeles International Airport 12:15
        BUFBuffalo Airport 06:45
      • SFOSan Francisco International Airport 13:43
        DFWDallas/Fort Worth Intl Airport 09:04
      • 9h 58m (1h 54m)
      • 1 Stop SFO · San Francisco 1h 54m
      • American Airlines (AA 6196)Embraer Emb 175
        American Airlines (AA 576)Airbus
      • American Airlines (AA 6196)
        • -
        • -
        • -
        • -
        • F
        • -
        • -
      • 12:15 LAX
        09:04 DFW
        9Hrs, 58m 1 Stop (SFO)
      • LAXLos Angeles International Airport 12:15 - DFW 09:04 9h 58m 1 Stop (SFO) San Francisco
      • LAXLos Angeles International Airport 12:15
        BUFBuffalo Airport 06:45
      • SFOSan Francisco International Airport 13:43
        DFWDallas/Fort Worth Intl Airport 09:04
      • 9h 58m (1h 54m)
      • 1 Stop SFO · San Francisco 1h 54m
      • American Airlines (AA 6196)Embraer Emb 175
        American Airlines (AA 576)Airbus
      • American Airlines (AA 6196)
        • M
        • T
        • W
        • T
        • -
        • S
        • S
      • 06:45 BUF
        14:58 SFO
        11Hrs, 13m 1 Stop (DFW)
      • BUFBuffalo Airport 06:45 - SFO 14:58 11h 13m 1 Stop (DFW) Dallas
      • BUFBuffalo Airport 06:45
        DFWDallas/Fort Worth Intl Airport 13:14
      • DFWDallas/Fort Worth Intl Airport 09:04
        SFOSan Francisco International Airport 14:58
      • 11h 13m (4h 10m)
      • 1 Stop DFW · Dallas 4h 10m
      • American Airlines (AA 576)Airbus
        American Airlines (AA 2177)Airbus
      • American Airlines (AA 576)
        • M
        • T
        • W
        • T
        • -
        • S
        • S
      • 06:45 BUF
        14:58 SFO
        11Hrs, 13m 1 Stop (DFW)
      • BUFBuffalo Airport 06:45 - SFO 14:58 11h 13m 1 Stop (DFW) Dallas
      • BUFBuffalo Airport 06:45
        DFWDallas/Fort Worth Intl Airport 13:14
      • DFWDallas/Fort Worth Intl Airport 09:04
        SFOSan Francisco International Airport 14:58
      • 11h 13m (4h 10m)
      • 1 Stop DFW · Dallas 4h 10m
      • American Airlines (AA 576)Airbus
        American Airlines (AA 2177)Airbus
      • American Airlines (AA 576)
        • -
        • -
        • -
        • -
        • F
        • -
        • -
      • 07:00 BUF
        15:31 SFO
        11Hrs, 31m 1 Stop (BOS)
      • BUFBuffalo Airport 07:00 - SFO 15:31 11h 31m 1 Stop (BOS) Boston
      • BUFBuffalo Airport 07:00
        BOSBoston Logan International Airport 12:00
      • BOSBoston Logan International Airport 08:24
        SFOSan Francisco International Airport 15:31
      • 11h 31m (3h 36m)
      • 1 Stop BOS · Boston 3h 36m
      • JetBlue Airways (B6 716)Embraer Emb E90
        JetBlue Airways (B6 733)Airbus Industrie A321
      • JetBlue Airways (B6 716)
        • M
        • T
        • W
        • T
        • F
        • -
        • S
      • 07:00 BUF
        11:21 SFO
        7Hrs, 21m 1 Stop (ORD)
      • BUFBuffalo Airport 07:00 - SFO 11:21 7h 21m 1 Stop (ORD) Chicago
      • BUFBuffalo Airport 07:00
        ORDChicago O'Hare International Airport 08:45
      • ORDChicago O'Hare International Airport 07:51
        SFOSan Francisco International Airport 11:21
      • 7h 21m (54m)
      • 1 Stop ORD · Chicago 54m
      • United Airlines (UA 329)Boeing 737 800
        United Airlines (UA 1983)Boeing 777
      • United Airlines (UA 329)
        • M
        • T
        • W
        • T
        • F
        • S
        • S
      • 07:00 BUF
        13:08 SFO
        9Hrs, 08m 1 Stop (ORD)
      • BUFBuffalo Airport 07:00 - SFO 13:08 9h 08m 1 Stop (ORD) Chicago
      • BUFBuffalo Airport 07:00
        ORDChicago O'Hare International Airport 10:40
      • ORDChicago O'Hare International Airport 07:51
        SFOSan Francisco International Airport 13:08
      • 9h 08m (2h 49m)
      • 1 Stop ORD · Chicago 2h 49m
      • United Airlines (UA 329)Boeing 737 800
        United Airlines (UA 343)Boeing 777
      • United Airlines (UA 329)
        • -
        • -
        • -
        • T
        • F
        • -
        • -
      • 11:36 DEN
        07:51 ORD
        9Hrs, 18m 1 Stop (SFO)
      • DENDenver Intl Airport 11:36 - ORD 07:51 9h 18m 1 Stop (SFO) San Francisco
      • DENDenver Intl Airport 11:36
        BUFBuffalo Airport 07:00
      • SFOSan Francisco International Airport 13:18
        ORDChicago O'Hare International Airport 07:51
      • 9h 18m (2h)
      • 1 Stop SFO · San Francisco 2h
      • United Airlines (UA 1561)Boeing 737 900
        United Airlines (UA 329)Boeing 737 800
      • United Airlines (UA 1561)
        • M
        • T
        • W
        • T
        • F
        • S
        • S
      • 07:00 BUF
        13:20 SFO
        9Hrs, 20m 1 Stop (ORD)
      • BUFBuffalo Airport 07:00 - SFO 13:20 9h 20m 1 Stop (ORD) Chicago
      • BUFBuffalo Airport 07:00
        ORDChicago O'Hare International Airport 10:40
      • ORDChicago O'Hare International Airport 07:51
        SFOSan Francisco International Airport 13:20
      • 9h 20m (2h 49m)
      • 1 Stop ORD · Chicago 2h 49m
      • United Airlines (UA 329)Boeing 737 800
        United Airlines (UA 343)Airbus A321 Neo
      • United Airlines (UA 329)
        • M
        • T
        • W
        • -
        • -
        • S
        • S
      • 12:28 BOI
        07:51 ORD
        9Hrs, 25m 1 Stop (SFO)
      • BOIBoise Airport 12:28 - ORD 07:51 9h 25m 1 Stop (SFO) San Francisco
      • BOIBoise Airport 12:28
        BUFBuffalo Airport 07:00
      • SFOSan Francisco International Airport 13:25
        ORDChicago O'Hare International Airport 07:51
      • 9h 25m (1h 35m)
      • 1 Stop SFO · San Francisco 1h 35m
      • United Airlines (UA 4733)Embraer 175
        United Airlines (UA 329)Boeing 737 800
      • United Airlines (UA 4733)
        • M
        • T
        • W
        • -
        • F
        • -
        • S
      • 07:00 BUF
        13:50 SFO
        9Hrs, 50m 1 Stop (JFK)
      • BUFBuffalo Airport 07:00 - SFO 13:50 9h 50m 1 Stop (JFK) New York City
      • BUFBuffalo Airport 07:00
        JFKNew York John F. Kennedy International Airport 10:30
      • JFKNew York John F. Kennedy International Airport 08:31
        SFOSan Francisco International Airport 13:50
      • 9h 50m (1h 59m)
      • 1 Stop JFK · New York City 1h 59m
      • Delta Air Lines (DL 5284)Canadair Regional
        Delta Air Lines (DL 1056)Boeing 757 200 Winglets
      • Delta Air Lines (DL 5284)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 07:00 BUF
        14:17 SFO
        10Hrs, 17m 1 Stop (JFK)
      • BUFBuffalo Airport 07:00 - SFO 14:17 10h 17m 1 Stop (JFK) New York City
      • BUFBuffalo Airport 07:00
        JFKNew York John F. Kennedy International Airport 11:00
      • JFKNew York John F. Kennedy International Airport 08:31
        SFOSan Francisco International Airport 14:17
      • 10h 17m (2h 29m)
      • 1 Stop JFK · New York City 2h 29m
      • Delta Air Lines (DL 5284)Canadair Regional
        Delta Air Lines (DL 680)Boeing 757 200 Winglets
      • Delta Air Lines (DL 5284)
        • -
        • -
        • -
        • -
        • -
        • -
        • S
      • 07:00 BUF
        14:19 SFO
        10Hrs, 19m 1 Stop (JFK)
      • BUFBuffalo Airport 07:00 - SFO 14:19 10h 19m 1 Stop (JFK) New York City
      • BUFBuffalo Airport 07:00
        JFKNew York John F. Kennedy International Airport 10:59
      • JFKNew York John F. Kennedy International Airport 08:31
        SFOSan Francisco International Airport 14:19
      • 10h 19m (2h 28m)
      • 1 Stop JFK · New York City 2h 28m
      • Delta Air Lines (DL 5284)Canadair Regional
        Delta Air Lines (DL 680)Boeing 757 200 Winglets
      • Delta Air Lines (DL 5284)
        • -
        • -
        • W
        • T
        • -
        • -
        • -
      • 07:00 BUF
        14:19 SFO
        10Hrs, 19m 1 Stop (JFK)
      • BUFBuffalo Airport 07:00 - SFO 14:19 10h 19m 1 Stop (JFK) New York City
      • BUFBuffalo Airport 07:00
        JFKNew York John F. Kennedy International Airport 10:59
      • JFKNew York John F. Kennedy International Airport 08:29
        SFOSan Francisco International Airport 14:19
      • 10h 19m (2h 30m)
      • 1 Stop JFK · New York City 2h 30m
      • Delta Air Lines (DL 5284)Canadair Regional
        Delta Air Lines (DL 680)Boeing 757 200 Winglets
      • Delta Air Lines (DL 5284)
        • M
        • T
        • -
        • -
        • F
        • -
        • -
      • 07:05 BUF
        13:15 SFO
        9Hrs, 10m 1 Stop (PHX)
      • BUFBuffalo Airport 07:05 - SFO 13:15 9h 10m 1 Stop (PHX) Phoenix
      • BUFBuffalo Airport 07:05
        PHXPhoenix Sky Harbor Intl Airport 11:15
      • PHXPhoenix Sky Harbor Intl Airport 08:35
        SFOSan Francisco International Airport 13:15
      • 9h 10m (2h 40m)
      • 1 Stop PHX · Phoenix 2h 40m
      • Southwest Airlines (WN 1094)Boeing 737 700
        Southwest Airlines (WN 3523)Boeing 737 800
      • Southwest Airlines (WN 1094)
        • -
        • -
        • -
        • -
        • -
        • -
        • S
      • 07:05 BUF
        14:30 SFO
        10Hrs, 25m 1 Stop (LAS)
      • BUFBuffalo Airport 07:05 - SFO 14:30 10h 25m 1 Stop (LAS) Las Vegas
      • BUFBuffalo Airport 07:05
        LASLas Vegas McCarran International Airport 12:50
      • LASLas Vegas McCarran International Airport 08:45
        SFOSan Francisco International Airport 14:30
      • 10h 25m (4h 05m)
      • 1 Stop LAS · Las Vegas 4h 05m
      • Southwest Airlines (WN 4085)Boeing 737 Max 8 Passenger
        Southwest Airlines (WN 2876)Boeing 737 700
      • Southwest Airlines (WN 4085)
        • M
        • -
        • -
        • T
        • F
        • -
        • -
      • 07:25 BUF
        13:21 SFO
        8Hrs, 56m 1 Stop (JFK)
      • BUFBuffalo Airport 07:25 - SFO 13:21 8h 56m 1 Stop (JFK) New York City
      • BUFBuffalo Airport 07:25
        JFKNew York John F. Kennedy International Airport 09:55
      • JFKNew York John F. Kennedy International Airport 08:50
        SFOSan Francisco International Airport 13:21
      • 8h 56m (1h 05m)
      • 1 Stop JFK · New York City 1h 05m
      • JetBlue Airways (B6 2001)Airbus A220 300
        JetBlue Airways (B6 115)Airbus Industrie A321
      • JetBlue Airways (B6 2001)
        • M
        • T
        • W
        • T
        • F
        • S
        • S
      • 07:25 BUF
        14:15 SFO
        9Hrs, 50m 1 Stop (JFK)
      • BUFBuffalo Airport 07:25 - SFO 14:15 9h 50m 1 Stop (JFK) New York City
      • BUFBuffalo Airport 07:25
        JFKNew York John F. Kennedy International Airport 11:00
      • JFKNew York John F. Kennedy International Airport 08:50
        SFOSan Francisco International Airport 14:15
      • 9h 50m (2h 10m)
      • 1 Stop JFK · New York City 2h 10m
      • JetBlue Airways (B6 2001)Airbus A220 300
        JetBlue Airways (B6 1515)Airbus Industrie A321
      • JetBlue Airways (B6 2001)
        • M
        • T
        • W
        • T
        • F
        • -
        • S
      • 07:25 BUF
        14:16 SFO
        9Hrs, 51m 1 Stop (JFK)
      • BUFBuffalo Airport 07:25 - SFO 14:16 9h 51m 1 Stop (JFK) New York City
      • BUFBuffalo Airport 07:25
        JFKNew York John F. Kennedy International Airport 11:00
      • JFKNew York John F. Kennedy International Airport 08:50
        SFOSan Francisco International Airport 14:16
      • 9h 51m (2h 10m)
      • 1 Stop JFK · New York City 2h 10m
      • JetBlue Airways (B6 2001)Airbus A220 300
        JetBlue Airways (B6 1515)Airbus Industrie A321
      • JetBlue Airways (B6 2001)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 07:30 BUF
        11:40 SFO
        7Hrs, 10m 1 Stop (DEN)
      • BUFBuffalo Airport 07:30 - SFO 11:40 7h 10m 1 Stop (DEN) Denver
      • BUFBuffalo Airport 07:30
        DENDenver Intl Airport 10:00
      • DENDenver Intl Airport 08:55
        SFOSan Francisco International Airport 11:40
      • 7h 10m (1h 05m)
      • 1 Stop DEN · Denver 1h 05m
      • Southwest Airlines (WN 621)Boeing 737 800
        Southwest Airlines (WN 549)Boeing 737 Max 8 Passenger
      • Southwest Airlines (WN 621)
        • -
        • T
        • W
        • -
        • -
        • -
        • -
      • 07:45 BUF
        14:29 SFO
        9Hrs, 44m 1 Stop (ORD)
      • BUFBuffalo Airport 07:45 - SFO 14:29 9h 44m 1 Stop (ORD) Chicago
      • BUFBuffalo Airport 07:45
        ORDChicago O'Hare International Airport 11:45
      • ORDChicago O'Hare International Airport 08:33
        SFOSan Francisco International Airport 14:29
      • 9h 44m (3h 12m)
      • 1 Stop ORD · Chicago 3h 12m
      • American Airlines (AA 2164)Boeing 737 800
        American Airlines (AA 2765)Boeing 737 800
      • American Airlines (AA 2164)
        • M
        • T
        • W
        • T
        • F
        • S
        • S
      • 13:05 LAS
        08:33 ORD
        9Hrs, 58m 1 Stop (SFO)
      • LASLas Vegas McCarran International Airport 13:05 - ORD 08:33 9h 58m 1 Stop (SFO) San Francisco
      • LASLas Vegas McCarran International Airport 13:05
        BUFBuffalo Airport 07:45
      • SFOSan Francisco International Airport 14:43
        ORDChicago O'Hare International Airport 08:33
      • 9h 58m (2h 29m)
      • 1 Stop SFO · San Francisco 2h 29m
      • Alaska Airlines (AS 375)Boeing 737 Max 9 Passenger
        American Airlines (AA 2164)Boeing 737 800
      • Alaska Airlines (AS 375)
        • -
        • -
        • -
        • -
        • -
        • -
        • S
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      What’s the most popular airline flying from Buffalo to San Francisco?

      The most popular airline flying from Buffalo to San Francisco is Frontier Airlines. Find the latest flight deals on Wego.

      How far is San Francisco from Buffalo?

      The flight distance between Buffalo and San Francisco is 3693km. Check all available flights on Wego.

      When is the earliest and latest flight of the day?

      The earliest flight of the day departs at 06:00. The last flight of the day departs at 06:00. See the full list of flight times on Wego.

      All Airports in Buffalo

      Buffalo Airport BUF

      All Airports in San Francisco

      San Francisco International Airport SFO

      Popular Airlines flying from Buffalo to San Francisco

      Frontier Airlines ‏()

      Popular Destinations from San Francisco

      Popular Destinations from Buffalo

      Popular Hotels in San Francisco

      Hotels In Popular Destinations